A short Florence itinerary should stay anchored to Piazza del Duomo, where the Florence Cathedral (Duomo di Firenze) dominates the skyline with its famous dome and marble facade just steps from Ponte Vecchio, the medieval bridge lined with jewelers over the Arno. From there, the Uffizi Gallery and Accademia Gallery hold the Renaissance masterpieces, including Michelangelo's David, while Piazza della Signoria offers open-air sculpture and cafe views. Together these five sights cover Florence's essential art, architecture, and street life within easy walking distance, making them the smartest priorities when time is limited.