Milan rewards a short visit if you keep to the essentials. The Duomo di Milano anchors everything, its marble spires visible across the city, and it sits right on Piazza del Duomo alongside the glass-vaulted Galleria Vittorio Emanuele II, Italy's grandest shopping arcade. A short walk away, Santa Maria delle Grazie holds Leonardo's Last Supper, a fresco that demands advance booking but rewards it completely. Add Lake Como for an easy day trip and the Milan Metro to move between them efficiently, and you've covered the historic center, a Renaissance masterpiece, and the surrounding region without wasted time.