Architecturally stunning octagonal basilica completed in 1681, a masterpiece of Baroque design sitting where the Grand Canal meets Giudecca Canal. Built as a votive church for plague deliverance, the luminous interior features Titian paintings including ceiling roundels in the sacristy. Open daily 9:30 AM–5:30 PM (Nov–Mar until 5 PM). €3 admission. The unique octagonal shape and sweeping dome are best appreciated from outside; interior provides quiet refuge from crowds.