Grodno is well-connected by rail and bus to major Belarusian cities and neighboring countries, situated near the Polish and Lithuanian borders, making it an excellent base for regional exploration.
The Grodno Railway Station is itself a notable Soviet-era architectural landmark with a grand neoclassical facade built in the 1950s. It serves as the main transportation hub connecting Grodno to Minsk (4–5 hours), Brest, and international destinations in Poland and Lithuania. International trains require a border crossing stop with passport control — allow extra time for these journeys.